David Bellamy is an Infrastructure Engineer for agentic training and a Harvard PhD Statistician, that I follow on X.
I hope he doesn’t mind that I quote him verbatim here.
I must be among an extremely small group of people (n=1?) that have both 1) trained a frontier LLM and 2) designed and synthesized custom viruses in a lab with my own two hands.
And I think that the takes on AI killing us all by creating dangerous viruses is total bogus.
Could an LLM propose a viral genome to synthesize? Sure. Could it be synthesize-able? Sure. Could it be infectious? Sure, it could just be a replica or a slight modification of a viral genome we already know.
This really isn’t the bottleneck to creating dangerous viruses. The bottleneck is in the physical process of synthesizing a virus and the equipment/goods needed to do so.
Designing a virus that can evade all forms of pandemic counterdefense is not something that a ‘genius in a datacenter’ can do. This is something that requires contact with the physical world and iteration.
Let me steelman the fearmongering as much as I can. Imagine a ‘fully automated’ viral synthesis laboratory. I’m talking automated freezers, automated cell culture room, the whole nine yards. This would be an extremely expensive lab – >>$100M. And there is no such thing as 1 lab that can synthesize all conceivable viruses. But let’s put practical constraint aside. Let’s suppose this hypothetical lab is built to synthesize the ‘most dangerous types’ of viruses known.




